Sepax SRT-C, Zenix-C, and Unix-C - High-Performance HPLC Columns for Size Exclusion Chromatography

SRT-C, Zenix-C and Unix-C columns are silica based columns. Like the SRT, Zenix and Unix phases, the SRT-C, Zenix-C and Unix-C particles are coated with an uniform, hydrophilic and neutral film. However, this monolayer is a lay-down layer instead of a stand-up monolayer.

Schematic representation of the differences between SRT-C and Zenix-C phases and SRT and Zenix

This is ideal for the separation of all biological samples types including challenging hydrophobic samples like antibody drug conjugates (ADCs), hydrophobic mAb and its fragments, bispecific mAbs (BsMAbs), PEGylated proteins, glycoproteins, fusion proteins, membrane proteins and oligonucleotides.

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Technical Data

SRT-C

Phase	Particle size	Pore size	Molecular range
SRT-C SEC-100	5, 10 μm	100 Å	100 - 100,000 (100 - 30,000 for 10 μm particle) Da
SRT-C SEC-150	5 μm	150 Å	500 - 150,000 Da
SRT-C SEC-300	5, 10 μm	300 Å	5,000 - 1,250,000 Da
SRT-C SEC-500	5, 10 μm	500 Å	15,000 - 5,000,000 Da
SRT-C SEC-1000	5, 10 μm	1000 Å	50,000 - 7,500,000 Da
SRT-C SEC-2000	5 μm	2000 Å	>10,000,000 Da

Zenix-C

Phase	Particle size	Pore size	Molecular range
Zenix-C SEC-80	3 μm	80 Å	100 - 50,000 Da
Zenix-C SEC-100	3 μm	100 Å	100 - 100,000 Da
Zenix-C SEC-150	3 μm	150 Å	500 - 150,000 Da
Zenix-C SEC-300	3 μm	300 Å	5,000 - 1,250,000 Da