Capcell-Core is a brand name for various core-shell (fused-core™) phases of the Japanese manufacturer Osaka-Soda. Previously, the columns belonged to the Shiseido Company, whose chromatography division was acquired by Osaka Soda in 2017. Capcell Core is a polymer-coating type core-shell (fused-core™) column of 2.7-µm particle with 1.7-µm solid core and 0.5-µm porous layer. Capcell Core provides high-speed and improved separation in UHPLC as well as conventional HPLC.
Phase-Name | Modification | Particle Size | Pore Size | End-capping | C-Content | USP | Surface | pH-Range | Tmax |
Capcell Core AQ | C27 | 2.7 µm | 160 Å | + | 4% | N/A | 90 m2/g | 2.0-10.0 | N/A |
Capcell Core C18 | C18 | 2.7 µm | 90 Å | + | 7% | L1 | 150 m2/g | 1.5-10.0 | N/A |
Capcell Core MP | C18 | 2.7 µm | 160 Å | + | 5% | L1 | 90 m2/g | 2.0-10.0 | N/A |
Capcell Core WP | C18 | 2.7 µm | 300 Å | + | 1.3% | L1 | 40 m2/g | 2.0-10.0 | N/A |
Capcell Core PFP | Pentafluorophenyl | 2.7 µm | 90 Å | + | 5% | L43 | 150 m2/g | 2.0-9.0 | N/A |
Capcell Core ADME | Adamantyl | 2.7 µm | 90 Å | + | N/A | N/A | 150 m2/g | 2.0-9.0 | N/A |
Capcell Core PC | Phosphoryl choline | 2.7 µm | 90 Å | N/A | N/A | N/A | 150 m2/g | 2.0-7.5 | N/A |
Determination of acrylamide with CAPCELL CORE PC S2.7.
1. Acrylamide
Test Conditions:
Column: CAPCELL CORE PC S2.7 ; 2.1 mm i.d. x 150 mm
Mobile Phase: 0.1 vol% HCOOH / CH3CN = 10 / 90
Flow rate: 200 µL/min
Temperature: 40°C
Detection: HPLC-MS
Ionization: ESI +
Injection volume: 2 µL
Sample: Standard was dissolved in water at 1 mg/mL, and then diluted to1 µg/mL with 80 vol% CH3CN