MicroSolv / Cogent
Cogent
Cogent HPLC Column™ from the US manufacturer Microsolv™ Tech. Corp. based on the unique silica hydride technology. The stationary phase is formed from a high purity Type B silica backbone, which is modified to cover the silica surface with silicon-hydride (Si-H) bonds, thus replacing >95% of surface silanols (Si-OH). As a result, Cogent Type-C™ particles have only a weakly associated water shell. Using patented technology, various bonded phases are produced from the unique silica hydride surface with direct silicon-carbon bonds. These extremely strong non-polar bonds offer increased stability over traditional silica based phases.
Cogent HPLC columns™ can be used in three different modes of HPLC: (1.) Classic reversed-phase (RP), (2.) Normal-phase with non-polar solvents, such as hexane, and (3.) Normal-phase with aqueous eluents (ANP). Further advantages of these phases are fast equilibration between gradient runs, unique retention and selectivity properties, and excellent suitability for LC-MS.
| Phase-Name | Modification | Particle Size | Pore Size | End-capping | C-Content | USP | Surface | pH-Range | Tmax |
| Cogent Bidentate C18™ | C18 | 4 µm | 100 Å | - | 18−19% | L1 | 390 m2/g | 2.0−10.0 | 80 °C |
| Cogent Bidentate C18 2.ō™ | C18 | 2.2 µm | 120 Å | - | 20% |
| 340 m2/g | 2.0−10.0 | 80 °C |
| Cogent Bidentate C8™ | C8 | 4 µm | 100 Å | - | 13−14% |
| 390 m2/g | 2.0−8.0 | 80 °C |
| Cogent Bidentate C8 2.ō™ | C8 | 2.2 µm | 120 Å | - | 11−12% |
| 340 m2/g | 2.0−8.0 | 80 °C |
| Cogent Bidentate C8 300™ | C8 | 5 µm | 300 Å | - | 5% |
| 100 m2/g | 2.0−7.5 | 80 °C |
| Cogent Phenyl Hydride™ | Phenyl | 4 µm | 100 Å | - | 10−12% |
| 390 m2/g | 2.0−8.0 | 80 °C |
| Cogent Phenyl Hydride 2.ō™ | Phenyl | 2.2 µm | 120 Å | - | 9−10% |
| 340 m2/g | 2.0−8.0 | 80 °C |
| Cogent Diol™ | Diol | 4 µm | 100 Å | - | 9−10% |
| 390 m2/g | 2.0−8.0 | 80 °C |
| Cogent Diol 2.ō™ | Diol | 2.2 µm | 120 Å | - | 9−10% |
| 340 m2/g | 2.0−8.0 | 80 °C |
| Cogent Amide™ | Amide | 4 µm | 100 Å | - | 2−3% |
| 390 m2/g | 2.0−7.5 | 80 °C |
| Cogent Hydride™ | N/A | 4 µm | 100 Å | - | 2% |
| 390 m2/g | 2.0−7.5 | 80 °C |
| Cogent Hydride 2.ō™ | N/A | 2.2 µm | 120 Å | - | 2% |
| 340 m2/g | 2.0−7.5 | 80 °C |
| Cogent UDC-Cholesterol™ | Cholesterol | 4 µm | 100 Å | - | 13−14% |
| 390 m2/g | 2.0−8.0 | 80 °C |
| Cogent UDC-Cholesterol 2.ō™ | Cholesterol | 2.2 µm | 120 Å | - | 13−14% |
| 340 m2/g | 2.0−8.0 | 80 °C |
| Cogent UDA™ | Undecanoic Acid | 4 µm | 100 Å | - | 14−15% |
| 390 m2/g | 2.0−8.0 | 80 °C |
| Cogent UDA 2.ō™ | Undecanoic Acid | 2.2 µm | 120 Å | - | 14−15% |
| 340 m2/g | 2.0−8.0 | 80 °C |
| Cogent Silica-C™ | - | 4 µm | 100 Å | - | 0% |
| 390 m2/g | 2.0−7.0 | 60 °C |
| Cogent Silica-C 2.ō™ | - | 2.2 µm | 120 Å | - | 0% |
| 340 m2/g | 2.0−7.0 | 60 °C |
Microsolv Cogent Brochure