Supel-Carbon HPLC Columns - Merck Supelco Sigma-Aldrich

The Supel™ Carbon from Supelco™ (Merck) are based on porous graphitic carbon (PGC). These particles have a unique retention mechanism, that can retain polar compounds using reversed-phase chromatography conditions. Moreover, the resolution of isomers is possible. Supel Carbon HPLC-Columns are compatible with any polar and non-polar solvent. Furthermore, this series can be used at pH values between 1 and 14 at temperatures up to 250 °C. They are stable at pressures up to 700 bar.

Supel™ Carbon is considered an alternative to Thermo Fisher Scientific's Hypercarb packaging material.

Advantages of Supel™ Carbon:

High lot-to-lot reproducibility
Temperature and pressure stable
high pH stability (1-14)
Unique mechanism
Retention of polar substances without HILIC conditions

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Technical Data

When should Supel Carbon Chromatography columns be used?

For the analysis of highly polar analytes, which are not retained under RP Chromatography conditions
Fort he analysis of polar pesticides, underivatized amino acids, vitamin D metabolites, organic acids, nucleosides and carbonhydrates
Easier alternative against HILIC methods
Alternative against Thermo Fisher Hypercarb (higher lot-to-lot-reproducibility)

Phase-Name	Modification	Particle size	Pore size	Surface	pH-Range	Tmax	pmax
Supel Carbon	Porous graphitic carbon (PGC)	2.7 μm	200 Å	155 m²/g	1-14	250 °C	700 bar

Supel Carbon

Technical Data

When should Supel Carbon Chromatography columns be used?

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