Ghost Buster Columns

The Ghost Buster column is a newly developed Ghost-Guard column from Welch Materials, Shanghai. Ghost-Guard columns are special HPLC columns that effectively remove non-polar impurities from the mobile phase and thus solve the problem of unwanted ghost peaks or poor baselines. The unwanted ghost peaks can occur especially during a gradient or after a long run time of the system. When using the previous Ghost Buster column from Welch, obvious fluctuations in the baseline can sometimes occur during gradient elution. When using the new Ghost Buster II column, this problem is eliminated. The Ghost Buster II columns show a stronger retention of impurities due to an optimised stationary phase.

The Ghost Buster column is installed between the mixer (after the pump) and before the injector. The sample does not have to pass through the Ghost Guard column, as only non-polar impurities are to be removed from the mobile phase.