ProSwift

ProSwift™ are HPLC Columns for fast and high-resolution LC/MS separations in bottom-up protein identification, biomarker discovery, and systems biology applications. Columns for reversed-phase, ion-exchange and affinity chromatography are available.
 

ProSwift™ RP phases are on a monolithic polystyrene divinylbenzene copolymer. ProSwift™ C4 RP-5H and all other ProSwift™ phases are based on monolithic Polymethacrylate. Each monolith is a single cylindrical, sponge-like polymer rod containing an uninterrupted, interconnected network of flow-through channels of a specific pore size; ranging from small channel (1S), medium size channels (2H % 4H) to very large channel (3U). These channels combined with the monolith's nonporous surfaces result in fast mass transfer for high resolution and fast protein separations. The channels also produce low backpressure, allowing the use of higher linear velocities with minimal loss of resolution.
 

The ProSwift™ RP-4H and PepSwift™ polymer matrices differ with respect to crosslink and co-monomer ratio, which may result in different selectivity under comparable conditions.
 

The ProSwift ConA-1S affinity monolith column is designed for the highly efficient enrichment and purification of Concanavalin A binding glycans, glycopeptides and glycoproteins.