Hypersil™ is a proven stationary phase for HPLC with long tradition by Thermo Scientific™. Introduced in 1976, Hypersil™ phases are well-established and widely used in many HPLC methods worldwide. Classical Hypersil™ phases are based on Type A silica gel, whereas the newer Hypersil GOLD™ materials are based on high purity Type B silica. Both phases are available in a variety of modifications. Hypersil GOLD™ columns provide enhanced separation performance compared to classical Hypersil™ materials and are ideal for both HPLC and UHPLC.
Phase-Name | Modification | Particle Size | Pore Size | End-capping | C-Content | USP | Surface | pH-Range | Tmax |
Hypersil ODS | C18 | 3, 5 µm | 120 Å | + | 10% | L1 | 170 m2/g | 2‒8 | 60 °C |
Hypersil ODS-2 | C18 | 3, 5 µm | 80 Å | + | 11% | L1 | 220 m2/g | 2‒8 | 60 °C |
Hypersil BDS (Base deactivated silica) | C18 | 2.4, 3, 5 µm | 130 Å | + | 11% | L1 | 170 m2/g | 2‒8 | 60 °C |
Hypersil MOS | C8 | 5 µm | 120 Å | - | 6.5% | L7 | 170 m2/g | 2‒8 | 60 °C |
Hypersil MOS-2 | C8 | 5 µm | 120 Å | + | 6.5% | L7 | 170 m2/g | 2‒8 | 60 °C |
Hypersil SAS | C1 | 5 µm | 120 Å | + | 3% | L13 | 170 m2/g | 2‒8 | 60 °C |
Hypersil Phenyl | Phenyl | 5 µm | 120 Å | - | 5% | L11 | 170 m2/g | 2‒8 | 60 °C |
Hypersil Phenyl-2 | Phenyl | 5 µm | 120 Å | + | 5% | L11 | 170 m2/g | 2‒8 | 60 °C |
Hypersil CPS | Cyanopropyl | 3, 5 µm | 120 Å | - | 4% | L10 | 170 m2/g | 2‒8 | 60 °C |
Hypersil CPS-2 | Cyanopropyl | 5 µm | 120 Å | + | 4% | L10 | 170 m2/g | 2‒8 | 60 °C |
Hypersil APS-2 | Aminopropyl | 3, 5 µm | 120 Å | - | 1.9% | L8 | 170 m2/g | 2‒8 | 60 °C |
Hypersil SAX | Quaternary Amine | 5 µm | 120 Å | + | 3% | L14 | 170 m2/g | 2‒8 | 60 °C |
Hypersil Green PAH | Proprietary | 3, 5 µm | 120 Å | + | 13.5% | N/A | 170 m2/g | 2‒8 | 60 °C |
Hypersil Silica | - | 3, 5 µm | 120 Å | - | 0% | L3 | 170 m2/g | 2‒8 | 60 °C |