Merck Supelco (Sigma-Aldrich) / Supelcosil

Supelcosil

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Supelcosil™ is a family of HPLC columns, manufactured by Supelco™ (Sigma-Aldrich™). The Phases based on spherical type-A silica, which is available in many different modifications for various separation techniques, e.g. Reversed-Phase‒, Normal-Phase‒ or Ion-Exchange-Chromatography.

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Technical Data

Supelcosil™ LC-DB phases are specially deactivated for basic compounds. These columns provide good peak shape and high efficiency for organic bases.
 

Supelcosil™ ABZ+Plus is a polar-embedded phase with high deactivation and unique selectivity. ABZ+Plus enables high efficiency separations of acids, bases, zwitterions and other difficult compounds.
 

Supelcosil™ LC-18-S, LC-18-T and LC-PAH are application-specific columns for the analysis of nucleosides, nucleotides or polyaromatic hydrocarbons.
 

With the Supelcosil Hisep, there is also a mixed-mode column that possesses a shielded hydrophobic phase. Here, the silica-gel is coated by a thin polymer layer with hydrophobic regions in a hydrophilic network. Thus, small analytes can be retarded and proteins are excluded.

Phase-Name

Modification

Particle Size

Pore Size

End-capping

C-Content

USP

Surface / m2/g

pH-Range

Tmax

Supelcosil™ LC-18

C18

3, 5, 12 µm

120 Å

+

11%

L1

170

2.0‒7.5

70 °C

Supelcosil™ LC-18 DB

C18

3, 5 µm

120 Å

+

11%

L1

170

N/A

N/A

Supelcosil™ LC-18-S

C18

5 µm

120 Å

+

11%

L1

170

N/A

70 °C

Supelcosil™ LC-18-T

C18

3, 5 µm

120 Å

+

12.3%

L1

170

N/A

70 °C

Supelcosil™ LC-8

C8

3, 5 µm

120 Å

+

6%

L7

170

2.0‒7.5

70 °C

Supelcosil™ LC-8 DB

C8

3, 5 µm

120 Å

+

6%

L7

170

N/A

N/A

Supelcosil™ LC-1

C1

5 µm

120 Å

+

2%

L13

170

2.0‒7.5

70 °C

Supelcosil™ LC-DP

Diphenyl

5 µm

120 Å

+

6%

L11

170

2.0‒7.5

70 °C

Supelcosil™ LC-CN

Cyanopropyl

3, 5 µm

120 Å

+

4%

L10

170

2.0‒7.5

70 °C

Supelcosil™ LC-PCN

Cyanopropyl

5 µm

120 Å

+

4%

L10

170

N/A

N/A

Supelcosil™ LC-NH2

Aminopropyl

3, 5 µm

120 Å

+

3%

L8

170

2.0‒7.5

70 °C

Supelcosil™ LC-NH2-NP

Aminopropyl

5 µm

120 Å

+

3%

L8

170

2.0‒7.5

70 °C

Supelcosil™ LC-Diol

Diol

5 µm

120 Å

-

3.5%

L20

170

2.0‒7.5

70 °C

Supelcosil™ LC-F

Pentafluorophenyl

5 µm

120 Å

+

5%

L43

170

2.0‒7.5

70 °C

Supelcosil™ ABZ+Plus

Alkylamide

5 µm

120 Å

+

12%

L60

170

2.0‒7.5

70 °C

Supelcosil™ ABZ

Alkylamide

3, 5, 12 µm

120 Å

+

12%

L60

170

2.0‒7.5

70 °C

Supelcosil™ Suplex™ pKb-100

Alkylamide

5 µm

120 Å

-

12.5%

N/A

170

2.0‒7.5

70 °C

Supelcosil™ SAX1

Propyltrimethylammonium

5 µm

120 Å

N/A

12%

L14

170

N/A

N/A

Supelcosil™ LC-SCX

Propylsulfonic acid

5 µm

120 Å

N/A

N/A

L9

170

2.0‒7.5

70 °C

Supelcosil™ LC-PAH

C18

3, 5 µm

120 Å

N/A

N/A

N/A

N/A

N/A

N/A

Supelcosil™ LC-Si

-

3, 5, 12 µm

120 Å

-

-

L3

170

2.0‒7.5

70 °C

Supelcosil™ Hisep

Shielded hydrophobic phase

5 µm

120 Å

N/A

N/A

N/A

170

N/A

70 °C

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Applications

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