The Scherzo product range from Imtakt consists of three different mixed-mode HPLC columns for unique separations. The columns are well-suited for simultaneous analysis of polar and non-polar compounds. Both anionic and cationic compounds are retained on this columns. The following separation mechanisms can occur: Reversed-Phase, Anion‒ and Cation-Exchange.
Scherzo SS-C18: A large amount of strong ionic ligands loaded onto these ODS columns. They show improved retention of zwitterionic or weak ionic compounds.
Scherzo SM-C18: Weak ionic ligands adequately loaded onto these ODS columns. They are designed for the separation of basic/acidic compounds at neutral pH conditions.
Scherzo SW-C18: Only a low amount of strong ionic ligands loaded onto these ODS columns. They are effective for strong ionic compounds or basic compounds with formic acid containing eluents.
| Phase name | Modification | Particle size | Pore size | End-capping | C-content | USP | Surface area | pH range | Tmax |
| Scherzo SS-C18 | C18+SAX+SCX | 3 µm | 130 Å | N/A | N/A | N/A | N/A | N/A | N/A |
| Scherzo SM-C18 | C18+WAX+WCX | 3 µm | 130 Å | N/A | N/A | N/A | N/A | N/A | N/A |
| Scherzo SW-C18 | C18+SAX+SCX | 3 µm | 130 Å | N/A | N/A | N/A | N/A | N/A | N/A |
Imtakt Scherzo C18 Family Brochure