Helix Chromatography / Coresep

Coresep

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Coresep columns are mixed-mode phases on core-shell particles. Thus, these columns combine the unique selectivity of mixed-mode phases with the efficiency of core-shell particles.

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Technical Data

Phase

Modes

Particle size / μm

Pore size / Å

Coresep 100

Reversed phase


Cation exchange


Anion exclusion

2.7

90

Coresep S

HILIC


Cation exchange


Anion exclusion

2.7

90

Coresep SB

Reversal phase


Cation exclusion

2.7

90

Coresep 100

  • reversed phase column with embedded acidic ion-pairing groups
  • improved retention of basic compounds by cation-exchange
  • separates acidic compounds by ion exclusion
  • retains neutral compounds by reversed phase

 

Coresep S

  • normal phase column with embedded acidic ion-pairing groups
  • suitable for separation of sugars and other neutral or very polar compounds
  • separate compounds based on HILIC, cation-exchange and anion-exclusion
  • separates acidic compounds by ion exclusion
  • separate weak bases by ion-exchange

 

Coresep SB

  • reversed phase column with strong embedded basic ion-pairing groups
  • separate bases by ion-exclusion
  • retains neutral compounds by reversed phase
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